The Great New Wonderful

Olympia Dukakis

— Judy Hillerman

Jim Gaffigan

— Sandie

Judy Greer

— Allison Burbage

Maggie Gyllenhaal

— Emme Keeler

Tom McCarthy

— Davie Burbage

Sharat Saxena

— Satish

Naseeruddin Shah

— Avinash aka "Avi"

Tony Shalhoub

— Dr. Trabulous

Stephen Colbert

— Principal Peersall

Dick Latessa

— Jerry Binder

Will Arnett

— Danny Keeler

Seth Gilliam

— Clayton

Anita Gillette

— Lainie

Julie Dretzin

— Julie Driscoll

Edie Falco

— Safarah Polsky

Jim Parsons

— Justin

Rosemarie DeWitt

— Debbie

Alexis Dziena

— Angie (scenes deleted)