Jeremy Brett
— Sherlock Holmes
Edward Hardwicke
— Dr. John Watson
Juliet Aubrey
— Dolores
Roy Marsden
— John Stockton
Keith Barron
— Rob Ferguson
Elizabeth Spriggs
— Eileen Mason
Richard Dempsey
— Jack Ferguson
Maurice Denham
— Augustus Merridew
Jason Hetherington
— Michael Mason
Peter Geddis
— Mr. Gresty
Kate Lansbury
— Mrs. Gresty
Yolanda Vazquez
— Carlotta Ferguson
Maria Redmond
— Vera Gresty
Freddie Jones
— Pedlar
Hilary Mason
— Miss Ruddock
Stephen Tomlin
— PC Ware
Eileen O'Brien
— Mrs Carter
Andy Abrahams
— Mr. Carter
Marcello Walton
— Tom Carter
Paul Parris
— Albert, The Pageboy
Anthony Price
— Ricardo, The Baby