Clive Owen
— Devin O'Neil
Laura Linney
— Lily Magraw
Christien Anholt
— Terry O'Neil
Andre Braugher
— Lucius
Dan Futterman
— Shelby Peyton
Josh Lucas
— George Armstrong Custer
Penny Johnson Jerald
— Lavinia
Stephen Root
— Secretary of War Edwin Stanton
Len Cariou
— Dr. Leland Peyton
Beverly Todd
— Hannah
Paul Guilfoyle
— General Beauregard
Sophie Ward
— Shannon O'Neil
Dana Ivey
— Mrs. Julia Peyton
Mark Pellegrino
— Skinner
Lorraine Toussaint
— Sarah