Mary Pickford
— Pollyanna Whittier
Katherine Griffith
— Aunt Polly Harrington
Howard Ralston
— Jimmy Bean
Helen Jerome Eddy
— Nancy Thing
George Berrell
— Old Tom
William Courtleigh
— John Pendleton
Herbert Prior
— Dr. Tom Chilton
Wharton James
— Rev. John Whittier
Doc Crane
— Bit Role (uncredited)
Joan Marsh
— Bit Role (uncredited)
Frederick Peters
— Bit Role (uncredited)
Gordon Sackville
— Bit Role (uncredited)