Robert Vaughn
— Harry S. Truman
Arthur Kennedy
— Tom Pendergast
Martha Scott
— Mamma Truman
June Dayton
— Bess Truman
Russell Johnson
— Linaver
Ronne Troup
— Constance
Alan Fudge
— Mooney
James Luisi
— Stranger
Lou Frizzell
— Quilling
Leonard Stone
— Werner
Michael Vandever
— Lorenzo Dayton
Alice Backes
— Teacher
Tasha Lee
— Margaret Truman
Jay Virela
— Pete