Kamal Haasan
— Vishwanathan / Major Wisam Ahmad Kashmiri
Rahul Bose
— Omar Qureshi
Andrea Jeremiah
— Ashmita Subramaniam
Pooja Kumar
— Dr. Nirupama
Shekhar Kapur
— Colonel Jagannath
Jaideep Ahlawat
— Salim
Samrat Chakrabarti
— Deepak Chatterjee
Nassar
— Nassar
Zarina Wahab
— Nirupama's Psychiatrist
Miles Anderson
— Dr. Dawkins
Naren Weiss
— Osama bin Laden
Mukhtar Khan
— Farukh
James Babson
— Tom Black
Jude S. Walko
— Captain Joe Black
Chris Kotcher
— Tollbooth Operator
Greg Sammis
— FBI Agent
David Scott Diaz
— FBI Agent Dave
Rajesh M. Selva
— Abu
Atul Tiwari
— Detective Peter Manivannan
Abhirami
— Dr. Nirupama (Voice)