Marlon Wayans
— Danny Styles
Damon Wayans
— Charlie Richman
Jim Belushi
— Jeffrey Stone (as James Belushi)
Terry Crews
— Big James
Camryn Manheim
— Vicki Matters
Lochlyn Munro
— Greg Elese
Shakara Ledard
— Stacy
Katt Williams
— The Comic
Bob Saget
J.R. Cacia
— Doctor (as Joseph Cacia)
Jimmy Brogan
— Emcee
Patty Ross
George Wallace
Jessica Anderson
— Kissing Girl
Steven Bernstein
— British Reporter
Denise Boutte
— Lady at piano
Kimberly Fisher
— Charlie's Girl
Patrice Fisher
— Regina
Darcy Halsey
— Lady in Crowd
Jesse Colton Hopfer
— Little Danny
Paul Ogata
— Karate Man
Palma Lawrence Reed
— Danny's Mom
Kari Ruth
— Charlie's Girl
Douglas Sarine
— Heckler
Breanna Startzel
— Party Girl
Joseph Vassallo
— Homeless Man (as Joe Vassallo)