శంకర్ దాదా ఎం.బి.బి.ఎస్.

Chiranjeevi

— Shankar Prasad / Shankar Dada

శ్రీకాంత్

— ATM

Sonali Bendre

— Dr. Sunitha "Chitti"

Paresh Rawal

— Dr. J. Rama Lingeshwara Rao

Girish Karnad

— Satya Prasad

Venniradai Nirmala

— Shankar Prasad's mother

M. S. Narayana

— Dr. Chidambaram MBBS, FRCS

Surya Bhagawan Das

— Dr. Mohammed Rafi

Deepti Nallamothu

— Meena

Sharwanand

— Vijay

Panja Vaisshnav Tej

— Cameo Appearance as Child Artist

Ali Basha

— Thief

Ahuti Prasad

— Corrupted Doctor

Gauahar Khan

— Special appearance in song

Venu Madhav

— Malhotra, Shankar's henchmen

Tirupati Prakash

Chalapathi Rao

Bhupinder Singh

— Pandu Dada

Banerjee

— Corrupted Faculty

Narsing Yadav

— Shankar's henchmen

Thotapalli Madhu

Athili Lakshmi

Duvvasi Mohan

Karate Kalyani Padala

Anjala Zaveri

— Cameo Appearance in “Chaila Chaila” song

పవన్ కళ్యాణ్

— Special appearance in song