Richard Barthelmess
— Karl Brenner
Marian Marsh
— Lotti Brenner
Norman Foster
— Stephan Brenner
Adrienne Dore
— Anna
Lucille La Verne
— Martha Brenner, Karl's foster mother (as Lucille LaVerne)
John St. Polis
— Dr. Niergardt
George Rosener
— Dr. Von Bergman
Nigel De Brulier
— Autopsy Surgeon (uncredited)