Dev Anand
— Raju Guide
Waheeda Rehman
— Rosie Marco/Nalini
Leela Chitnis
— Raju's Mother
K.N. Singh
Anwar Hussain
— Ghaffoor
Rashid Khan
— Joseph
J.S. Casshyap
— as J.S. Cashyap
Kishore Sahu
— Marco
Dilip Dutt
— Mani
Iftekhar
— as Iftekhar
Ulhas
— Raju's Uncle
Krishan Dhawan
— Inspector Girdhari
