Steve Antin
— Monkey Zetterland
Patricia Arquette
— Grace
Sandra Bernhard
— Imogene
Sofia Coppola
— Cindy
Tate Donovan
— Brent Zetterland
Rupert Everett
— Sasha
Katherine Helmond
— Honor Zetterland
Bo Hopkins
— Mike Zetterland
Ricki Lake
— Bella the Stalker
Debi Mazar
— Daphne
Martha Plimpton
— Sofie
Robin Antin
— Waitress in Canters
Frances Bay
— Grandma
Luca Bercovici
— Boot Guy
Chuck Grieve
— Guy at Taco Stand
Lance Loud
— Psychiatrist
Nicholas Matus
— Young Monkey
Chris Nash
— Policeman
Louis J. Pearlman
— Warden / Observation Psychiatrist
Blair Tefkin
— Brent's Assistant
Marc Lafia
— Observation Psychiatrist
Melissa Sullivan
— Observation Psychiatrist
Lauren Zuckerman
— Observation Psychiatrist
Reuven Russell
— CPR Rabbi (uncredited)
Vivian Schilling
— Network Producer (uncredited)