Martha Plimpton
— Samantha
Dermot Mulroney
— Henry
Héctor Elizondo
— Walter
Mary Kay Place
— Marilyn
Ione Skye
— Elaine
Marvin Silbersher
— Milos
I.M. Hobson
— Father O'Rourke
Maryedith Burrell
— Charlotte Otto
Robert Picardo
— Neil Otto
Shay Astar
— Young Samantha
Cameron Williams
— Young Henry
Dody Goodman
— Mrs. Higgins
Randy Pelish
— Ed Perlmutter
Sandra Kinder
— Phyllis Perlmutter
Jack Blessing
— Herman Hathaway
Earl Boen
— Support Group Leader
Lora Staley
— TV Reporter
Karie Prescott
— Quartet Violist
Gabriel Martínez
— Quartet Violinist
Alan Toy
— Manpower Dispatcher
Pablo Bryant
— Ivan
Philip Tanzini
— College Boyfriend
Steve Wilcox
— College Boyfriend
David Rogge
— College Boyfriend
Taj Johnson
— College Boyfriend
Adam Biesk
— College Boyfriend
Bea Marcus
— Mrs. Schtumer
Eric Gilliland
— Hendricks