Annette Bening
— Narrator (voice)
Susan Collins
— Self
Kay Bailey Hutchison
— Self
Blanche Lincoln
— Self
Barbara Boxer
— Self
Mary Landrieu
— Self
Hillary Clinton
— Self
Olympia Snowe
— Self
Debbie Stabenow
— Self
Lisa Murkowski
— Self
Patty Murray
— Self
Dianne Feinstein
— Self
Barbara Mikulski
— Self
Elizabeth Dole
— Self
Maria Cantwell
— Self
Alanis Morissette
— Self
Alan K. Simpson
— Self (archive footage)
Carol Moseley Braun
— Self (archive footage)
George H. W. Bush
— Self (archive footage)
Bill Clinton
— Self (archive footage)
Bob Dole
— Self (archive footage)
Ted Kennedy
— Self (archive footage)
Harvey Milk
— Self (archive footage)
Arlen Specter
— Self (archive footage)