Carr Thompson
— Arthur Read (voice)
Daniel Brochu
— Buster Baxter (voice)
Luciano Rauso
— D. W. Read (voice)
Bailey Lauren
— Francine Frensky (voice)
Nichole Blanchard
— Muffy Crosswire (voice)
James Burkholder
— Alan "The Brain" Powers (voice)
Bruce Dinsmore
— Binky Barnes / David Read (voice)
Wendee Lee
— Prunella / Mary Moo Cow (voice)
Christine Lakin
— Jane Read (voice)
Marc Graue
— Mr. Kone (voice)
Madison Danielle
— Tommy Tibble (voice)
Max Burkholder
— Timmy Tibble (voice)
Chuck Buell
— Waiter (voice)
Michael Dawson
— Arena Tech (voice)
Doug Stone
— TV Detective (voice)
Dave Mallow
— TV Announcer (voice)
Lara Cody
— Baby Kate (voice)
Yvette Kaplan
— Pal (voice)
Mona Marshall
— Rosie (voice)