Bobby 'Wheezer' Hutchins
— Wheezer
Mary Ann Jackson
— Mary Ann
Allen 'Farina' Hoskins
— Farina
Jean Darling
— Jean
Norman Chaney
— Chubby
Harry Spear
— Harry
The Wonder Dog Pal
— Pete
Thomas Atkins
— Wheeler's Little Brother (unconfirmed)
Joe Cobb
— Joe (unconfirmed)
Billy O'Brien
— (unconfirmed)
Jackie Cooper
— Kid listening to Farina (uncredited)
Bobby Mallon
— Kid listening to Farina (uncredited)
Dora Dean
— Mrs.Dean - Mother (uncredited)
Eddie Dunn
— Eddie - Father (uncredited)
Lyle Tayo
— Nurse (uncredited)