Penrod and Sam

Leon Janney

— Penrod Schofield

Frank Coghlan Jr.

— Sam Williams

Margaret Marquis

— Marjorie Jones

Dorothy Peterson

— Mary Schofield

Billy Lord

— Georgie Hemingway Bassett

Michael Stuart

— Rodney Bitts

Jimmy Robinson

— Herman Washington

Robert Dandridge

— Verman Washington

Matt Moore

— Henry Schofield

Helen Beaudine

— Margaret Shofield

Johnny Arthur

— Mr. Bassett

Zasu Pitts

— Mrs. Bassett

Charles Sellon

— Mr. Bitts

Elizabeth Patterson

— Schoolteacher (uncredited)

Gertrude Howard

— Delia (uncredited)

Wade Boteler

— Mr. Williams (uncredited)

Betty Jane Graham

— 'Baby' Amy Rensdale (uncredited)

Beaudine Anderson

— Boy (uncredited)

Billy Byrne

— Pudge Brown (uncredited)

Gus Leonard

— Violinist at Birthday Party (uncredited)

Albert Schaefer

— Piggy Nelson (uncredited)

Dorothy Vernon

— Irate Mother at Birthday Party (uncredited)

Sidney Miller

— Maurice Levy (uncredited)