Takeshi Kusao
— Sho Fukamachi / Guyver
水谷優子
— Mizuki Segawa (voice)
Hideyuki Tanaka
— Agito Makishima / Guyver III (voice)
Hirotaka Suzuoki
— Masaki Murakami (voice)
梅津秀行
— Takasato (voice)
掛川裕彦
— Cronos Combatant A / Enzyme II
加藤精三
— Dr. Hamilcar Barcas (voice)
Hidekatsu Shibata
— Richard Guyot (voice)
Chieko Honda
— Natsuki Taga/ Barcas's Aide (voice)
塩屋浩三
— Tetsuro Segawa (voice)
川村万梨阿
— Shizu Onuma (voice)
Banjō Ginga
— Gaster (voice)
沢木郁也
— ZX-Tole (voice)
筈見純
— Genzo Makishima (voice)
Issei Futamata
— Aptom (voice)
Jūrōta Kosugi
— Elegen (voice)
鈴木勝美
— Announcer / Cronos Combatant (voice)
Hiroyuki Oshida
— Cronos Combatant (voice)
中博史
— Cronos Combatant (voice)
田中和実
— Aota (voice)