James Cagney
— Flicker Hayes, aka Jerry Allen
Joan Blondell
— Rose Lawrence
Victor Jory
— Nick Gardella
Frank Craven
— Pop Sims, aka Jim Parker
Sarah Padden
— Mrs. Gardella
Harold Huber
— J.C. Ward, Curly's Hitman
Russell Hopton
— Monk, Curly's Hitman
Ralf Harolde
— Frank 'Red' Deering
John Qualen
— Dutch, Santa Avila's Cabbie
Bradley Page
— Dan 'Danny' Curly
Samuel E. Hines
— Gassy
George Chandler
— Highway Service Station Counterman
James Eagles
— Whitey, the Driver
Sidney Bracey
— Waiter
Gino Corrado
— Pico, Cristobol Crewman
Edward Earle
— Hotel Clerk
Charles R. Moore
— Manhattan Turkish Bath Attendant
Dennis O'Keefe
— Man Leaving Courtroom
Willard Robertson
— Police Captain
Harry Seymour
— Garage Attendant
Eddie Shubert
— Tobacco Clerk
Lee Shumway
— Detective
Billy West
— Chick