Robert Downey Jr.
— Mr. Willowby
Leslie Nielsen
— Baxter
Stockard Channing
— Miss Adelaide
Kevin Clash
— Father Mouse (voice)
Julianne Buescher
— Beverly Mouse (voice)
David Rudman
— Ned Mouse (voice)
Steve Whitmire
— Kermit the Frog / Bear / Owl (voice)
Bill Barretta
— Bear (voice)
Bruce Lanoil
— Bear / Owl (voice)
Kevin Thompson
— Bear
Shari Weiser
— Bear
Tracey Thompson
— Bear