Edgar Bergen
— Edgar Bergen / Charlie McCarthy (voice)
Jim Jordan
— Fibber McGee
Marian Jordan
— Molly McGee
Lucille Ball
— Julie Patterson
Lee Bonnell
— Jerry
Dorothy Lovett
— Marge
Harold Peary
— Gildersleeve
Isabel Randolph
— Mrs. Uppington
Walter Baldwin
— Bill
Neil Hamilton
— Hilary Horton
Charles Halton
— Cudahy
Harlow Wilcox
— Mr. Collins
Spencer Charters
— Motel Manager
Jed Prouty
— Mayor
George Cleveland
— Kelsey
Louise Currie
— Jane (uncredited)
Dot Farley
— Mary Blaize (uncredited)
Sterling Holloway
— Rusty (uncredited)
Dorothy Lloyd
— Maisie / Matilda (uncredited)