Victor McLaglen
— Crusher McKay
Chester Morris
— Doctor Craig
Wendy Barrie
— Ann Grayson
Alan Hale
— Gallagher
Barry Fitzgerald
— Britches
Allan Lane
— Bilson
Halliwell Hobbes
— Captain Mathews
Cy Kendall
— Deadeyes
Paul Guilfoyle
— Wishart
John Wray
— Metcalfe
Emory Parnell
— Olaf
Adia Kuznetzoff
— Silvio
John Bleifer
— Kovac
Ted Billings
— Stoker (uncredited)
Eddie Bracken
— Junior officer (uncredited)
Tyler Brooke
— Ship Steward (uncredited)
Donald Douglas
— Ship's Officer (uncredited)
Grace Hayle
— Fat Passenger (uncredited)
Selmer Jackson
— San Francisco Port Doctor (uncredited)
Florence Lake
— Miss Smith - Dancing with Crusher (uncredited)
Arthur Loft
— Engineering Officer Dearborn (uncredited)
Walter Miller
— Ship's Officer (uncredited)
Frank Mills
— Crew Member (uncredited)
Miki Morita
— Chinese Stowaway (uncredited)
Jack O'Shea
— Navigator (uncredited)
Douglas Walton
— Engineering Officer Bates (uncredited)
Anthony Warde
— Crew Member (uncredited)
Ernest Whitman
— Professor - Black Stoker (uncredited)