Mark Brooks
— Lil Pimp (voice)
Bernie Mac
— Fruit Juice (voice)
William Shatner
— Tony Gold (voice)
Ludacris
— Weathers (voice)
Lil' Kim
— Sweet Chiffon (voice)
Jennifer Tilly
— Miss De La Croix (voice)
Carmen Electra
— Honeysack (voice)
Big Boy
— Nag Champa (voice)
Danny Bonaduce
— Ugly Midget (voice)
John C. McGinley
— Man Cub Master (voice)
Mystikal
— Geoffrey (voice)
Jill Talley
— Mom / Old Lady / Mary (voice)
Peter Gilstrap
— Skinny Peeps / Kevin / Bonny (voice)
Kevin Michael Richardson
— Smokey / Hans Dribbler / Peabo / Vanderbilt (voice)
Rudy Ray Moore
— Mr Slippers (voice)
David Spade
— Principal Nixon (voice)
Jennifer Christner
— Neckbrace Girl (voice)
Tom Kenny
— Hans Dribbler Announcer / Billy / Clancey / Adam 12 Cop (voice)
Jess Harnell
— Tony Gold Ad Announcer (voice)
Jack Shih
— Cabbie (voice)
W.K. Stratton
— Additional Voices (voice)
Pamela Tyson
— Additional Voices (voice)
Don Dullilove
— Additional Voices (voice)
Rachel Crane
— Additional Voices (voice)
Devika Parikh
— Additional Voices (voice)
Elisa Gabrielli
— Additional Voices (voice)
Billy 'Sly' Williams
— Additional Voices (voice)
Art Kimbro
— Additional Voices (voice)