Donald Sutherland
— Dr. Thomas Vrain
John Marley
— Edgar Fine
Sharon Acker
— Tilla Vrain
Mare Winningham
— Carol Severance
Jeff Goldblum
— Dr. Aldo Gehring
Michael Lerner
— Henry De Vici
Richard Blackburn
— Dr. Cutter
Michael C. Gwynne
— Jay Wingate
Robert Joy
— David Art
Allan F. Nicholls
— Dr. Basil Rents
Kate Trotter
— Mrs. Anderson
Lally Cadeau
— Anita, Vrain's Secretary
Stuart Gillard
— Dick Getts
Barbara Gordon
— Wanda, Vrain's Scrub Nurse
Samantha Langevin
— Mrs. Clure
Jessica Steen
— Tracy Vrain
Casey Stevens
— Larry Hammond