Dick Van Dyke
— Ed McCall
Mariette Hartley
— Katherine McCall
George Coe
— Kannon Rush
William Daniels
— Draper Wright
Monte Markham
— Tony Malgrado
Arthur Rosenberg
— Marty Zimmerman
George Wyner
— Dr. Irving Lefkowitz
Claudia Lonow
— Peggy McCall
Charles Bloom
— David McCall
Michael Cummings
— Bud McCall
Rhea Perlman
— Tawney Shapiro
Jeff Altman
— Harry
Bill Erwin
— Grandpa
Terri Berland
— Stewardess
Marianne McAndrew
— Diane
Ernie Lively
— Conductor
Susan Ruttan
— Woman Prude
Shannon Tweed
— Beautiful Woman
Ray Singer
— Doug
Jacques Aubuchon
— Dr. Simon
Sivi Aberg
— Housekeeper
Israel Juarbe
— Jose