James Allen Brewer
— Jimmy Thudpucker
Barbara Harris
— Joanie Caucus
Charles Levin
— Mark Slackmeyer
Rebecca Nelson
— Barbara Ann 'Boopsie' Boopstein
William Sloane Coffin
— The Reverend Scott Sloan
Jack Gilford
— Referee
Michelle Browne
— Jeannie
Richard Cox
— Zonker Harris (voice)
David Grant
— Mike Doonesbury (voice)
Richard Bruno
— B.D. (voice)
Mark Baker
— Kirby (voice)
Rick Elice
— Frank (voice) (as Eric Elice)
Will Jordan
— Sportscaster (voice)
Linda Baer
— Ellie (voice)
Eric Jaffe
— Howie (voice)
Thomas Baxton
— Rufus (voice)
Lenny Jackson
— Magus (voice)
Patrice Leftwich
— Virgin Mary (voice)
Ben Haley Jr.
— Calvin (voice)