Mahesh Babu
— Gautham
Kriti Sanon
— Sameera
Nassar
— Chandrashekhar's Co-Scientist
Kelly Dorji
— Antonio Rosarius
Pradeep Ram Singh Rawat
— Taxi Driver
Anand
— Chandrashekhar
Anu Hasan
— Kalyani
Sayaji Shinde
— Inspector John Basha
Posani Krishna Murali
— Gulab Singh
Srinivasa Reddy
— Police Constable
Ravi Varma
— Michael
Surya Bhagawan Das
— Gautham's Doctor
Gautham
— Gautham (Child Character)
David Corden
— Insp. Douglas
Naveen Polishetty
— Taxi Driver's Son
Banerjee
— Sameera's boss
Sophiya Chaudhary
— Special Appearance in 'London Babu' song
Kumud Pant
— Car Driver
Paul Blackwell
— Police Officer
