Richard Edson
— Joey Breaker
Cedella Marley
— Cyan Worthington
Erik King
— Hip Hop Hank
Gina Gershon
— Jenny Chaser
Philip Seymour Hoffman
— Wiley McCall
Mary Joy
— Esther Trigliani
Fred Fondren
— Alfred Moore
Olga Bagnasco
— Karina Danzi
Michael Imperioli
— Larry Metz
John Costelloe
— Randy Jeter
Sam Coppola
— Sid Kramer
Laurence Mason
— Lester White
Seth Gilliam
— Jeremy Brasher
Sunday Theodore
— Morrissa Marker
George Bartenieff
— Dean Milford
Parker Posey
— Irena Kildare
Bill Bellamy
— Ace Man
Christopher Logan Healy
— Mike Dale
Lewis Black
— Pete Grimm
Joe Gioco
— Karina's Manager
Larry Marx
— Agent in Audience
Beverly Burchett
— Mineola Waitress
Anthony Ventola
— Astro Waiter
Benjamin Starr
— Boy in Hospital
Timothy Britten Parker
— M.C. / King of Comedy
James Dickson
— Hollywood Producer
Alison Moir
— Sexy Girl
Randy Schein
— Mailroom Clerk (uncredited)