Bing Crosby
— Dr. Bill Remsen
Mary Carlisle
— Judy Marlowe
Beatrice Lillie
— Mrs. Lorelei Dodge-Blodgett
Andy Devine
— Officer Lawrence O'Roon
Rufe Davis
— Al (Zookeeper)
Laura Hope Crews
— Mrs. Minerva Twombling
Fred Keating
— Chris LeRoy
John Hamilton
— Insp. Bryce
Sterling Holloway
— Luke (Ice-Cream Man)
Henry Wadsworth
— Otis Eaton (The Drunk)
Franklin Pangborn
— Mr. Stenchfield (Store Clerk)
Harold Minjir
— Mr. Coldwater
William Austin
— Mr. Martingale
Gino Corrado
— Cazzatta
Harry Stubbs
— Police Captain
Frank Elliott
— Lorelei's Butler
Charles R. Moore
— Tooter, the Chauffeur
Louis Armstrong
— Trumpet Player
Charlene Arnold
— Dancer (uncredited)
Joanne Arnold
— Dancer (uncredited)
Dolores Casey
— Nurse (uncredited)
Desmond Gallagher
— Stage Manager (uncredited)
Alphonse Martell
— Marvelous Marko (uncredited)
Allen Mathews
— LeRoy's Henchman (uncredited)
Gretchen McCarthy
— Dancer (uncredited)
Emory Parnell
— Sgt. Olson (uncredited)
Robert Taylor
— Band Member (uncredited)