Jessica Lange
— Dr. Cornelia Wilbur
Tammy Blanchard
— Sybil Dorset
JoBeth Williams
— Hattie Dorsett
Alison Murray
— Young Sybil
Fab Filippo
— Ramon
Brian Downey
— Willard
Brianna MacDonald
— Young Lulu
Joey Campbell
— University Student
David Patrick Flemming
— Young Doctor (as David Flemming)
Michael Ray Fox
— University Student (as Michael Fox)
Gary Levert
— Art teacher
Liam McNamara
— Tommy
Marlane O'Brien
— Bartender
Wanda Taylor
— Restaurant customer
Ron White
— Dr. Atcheson