Henry Armstrong
— Henry Jackson
Willie Bryant
— Frank Harrison
Mae E. Johnson
— Jerry Jordan (as Mae Johnson)
Hamtree Harrington
— 'Windy' Butler
Canada Lee
— Speedy Joe Williams (Henry's Trainer)
Lionel Monagas
— Eddie 'Ed' Watson (Henry's Manager)
Francine Everett
— Fanny Singleton
Dooley Wilson
— Baron Skinner (as Arthur 'Dooley' Wilson)