Lon Chaney
— Dr. Ziska
Johnny Arthur
— Johnny Goodlittle
Gertrude Olmstead
— Betty Watson
Hallam Cooley
— Amos Rugg
Charles Sellon
— Russ Mason
Walter James
— Caliban
Knute Erickson
— Daffy Dan
Frank Austin
— Rigo
Edward McWade
— Luke Watson
Ethel Wales
— Mrs. Watson
Elmo Billings
— Freckle Faced Kid (uncredited)
Herbert Prior
— Dr. Edwards (uncredited)
William H. Turner
— Detective Jennings (uncredited)
Dorothy Vernon
— Townswoman at Accident Scene (uncredited)