High School

Adrien Brody

— Psycho Ed

Matt Bush

— Henry Burke

Sean Marquette

— Travis Breaux

Colin Hanks

— Brandon Ellis

Michael Chiklis

— Dr. Leslie Gordon

Adhir Kalyan

— Sebastian Saleem

Mykelti Williamson

— Paranoid

Luis Chávez

— Big Dave

Max Van Ville

— Little Dave

Brett Kelly

— Martin Gordon

George Back

— Malcolm

Alicia Sixtos

— Sharky Ovante

Andrew Wilson

— Hippie Dude

Camille Mana

— Dana

Erica Vittina Phillips

— Tameka

Arcadiy Golubovich

— Edwin Hunter

Julia Ling

— Charlyne

Cody Longo

— Chad

Mary Birdsong

— Mrs. Gordon

Yeardley Smith

— Computer Skills Teacher

Curtis Armstrong

— Mr. Thompson

Alex Biats

— Spelling Bee Rival

John Beard

— Male News Desk Reporter

Barret Swatek

— Female News Desk Reporter

Rhys Coiro

— Vato

Wyatt Russell

— Drug PSA Stoned Teenager

Mike Eshaq

— Lead Terrorist

Heather Elizabeth Regan

— Cheerleader who collides with Henry

Terri Lyn Rodriguez

— Vivian

Robert Bailey Jr.

— Jeffrey