Michelle Williams
— Anna Watson
Meat Loaf
— Billy
Tim Guinee
— Tom
Louis Zorich
— Sammy
Bill Raymond
— Dr. Harold Ashton
Wendell Pierce
— Dan
Merritt Wever
— Betty
Jonathan Watton
— Bobby Watson
Ileen Getz
— Nurse Aphrodite
John Paul Tremblay
— Moe
Robb Wells
— Joe
Heidi von Palleske
— Cindy Watson
Jeremy Akerman
— Robert Watson Sr.
Gerry Mendicino
— Johnnie
John Dunsworth
— Pastor
Paul Macleod
— Preacher
Meaghan Hutchison
— Dopnna Frankel
Rhonda McLean
— Jane Frankel
Bruce Graham
— Frank Frankel
Gary Levert
— Mental Health Visitor
Dennis Brown
— Herman
Mark A. Owen
— Bartender
Shaun Clarke
— Tony the Toastmaster
Mike Smith
— Lobotomy Patient
Mark Day
— Mark (uncredited)
Marcus Shultz
— Bartender #2 (uncredited)