Richard Dreyfuss
— Prof. Krippendorf
Jenna Elfman
— Veronica
Zakes Mokae
— Sulukim
Siobhan Fallon Hogan
— Lori
Natasha Lyonne
— Shelly
Gregory Smith
— Mickey
Lily Tomlin
— Ruth Allen
Stephen Root
— Gerald Adams
Elaine Stritch
— Irene Hargrove
Mila Kunis
— Abbey Tournquist
David Ogden Stiers
— Henry Spivey
Doris Belack
— President Porter
Julio Oscar Mechoso
— Simon Alonso
Amzie Strickland
— Gladys Schmades
Phil Leeds
— Dr. Harvey
Frances Bay
— Edith Proxmire
Susan Ruttan
— Mrs. O'Brian
Tom Poston
— Gordon Hargrove
Penny Johnson Jerald
— Teacher
Bruce Jarchow
— Dr. Andrews, Chester Hill
Wendy Worthington
— Secretary
Carl Michael Lindner
— Edmund
Barbara Williams
— Jennifer
Sandy Martin
— Nurse
Lance Kinsey
— Principal Reese
Robin Karfo
— Mrs. Tournquist
Tim Halligan
— Mr. Tournquist
Peter Tilden
— Larry Swift
Shashawnee Hall
— Mabu
Timothy Wells
— Ruth's Guide