Billy Frankenstein

Jordan Lamoureux

— Billy Frankenstein

Mary Elizabeth McGlynn

— Sandy

Daran Norris

— George

Peter Spellos

— Bloodstone

Brian Carrillo

— Frankenstein

Kristin Jadrnicek

— Thelma

Vernon Wells

— Otto

Griffin Drew

— Fraulein

Tommy Kirk

— Blind Monk

Kimberly A. Ray

— Tour Guide

John Maynard

— Froog

Robert Burke

— Sheldon

Ernest Hardin Jr.

— Steve

Rick Cadelli

— Preston Strong

William Kuehn

— Chauffeur

Mark Thomas McGee

— Brain Vendor (as Mark McGee)

Andrew D'Amico

— Rat Vendor

Devan Scott

— Doll Vendor

Vanessa Greyshock

— Young Tourist Girl (as Vanessa A. Koman)

Marie Gutierrez

— Poor Mother

Sammy Drasin

— Poor Girl