Avery Brooks
— Uncle Tom
Kate Burton
— Ophelia
Bruce Dern
— Augustine St. Claire
Paula Kelly
— Cassy
Phylicia Rashād
— Eliza
Kathryn Walker
— Marie St. Claire
Edward Woodward
— Simon Legree
George Coe
— Mr. Shelby
Frank Converse
— Trader
Albert Hall
— Quimbo
Jenny Lewis
— Evangeline "Little Eva" St. Claire
Troy Byer
— Emmeline
Shirley Jo Finney
— Aunt Chloe
Samuel L. Jackson
— George
Endyia Kinney-Sterns
— Topsy
Lane Trippe
— Mrs. Shelby
Irma P. Hall
— Mammy
Jerry Haynes
— Dr. Phillips
Gil Glasgow
— Loker
Harlan Jordan
— Deputy
Paul Osborne
— Sambo
Sami Chester
— Sam
Rickey Pierre
— Andy
Gerald Hopkins
— Christopher at 17
Eliott Keener
— Auctioneer
B.J. Hopper
— Simeon
Robert Adams
— Phineas Fletcher
Carol Sutton
— Lucy
James Williamson
— Mark
Elaine Partnow
— Mrs. Smythe