It's Pat

Julia Sweeney

— Pat Riley

Dave Foley

— Chris

Charles Rocket

— Kyle Jacobsen

Kathy Griffin

— Kathy Griffin

Julie Hayden

— Stacy Jacobsen

Timothy Stack

— Doctor

Mary Scheer

— Nurse

Beverly Leech

— Mrs. Riley

Kathy Najimy

— Tippy

Larry Hankin

— Postal Supervisor

Michael Melchiondo Jr.

— Dean Ween

Aaron Freeman

— Gene Ween

Jerry Tondo

— Sushi Chef

Philip McNiven

— Sushi Customer

Michael Yama

— Curious Sushi Man

Kiyoko Yamaguchi

— Curious Sushi Woman

Arleen Sorkin

— Arleen Sorkin

Camille Paglia

— Camille Paglia

Phil LaMarr

— Stage Manager

Katie Wright

— Groupie

Robin Mary Florence

— Concert Party Waitress

Bobby McGee

— Hood

David Drake

— Gunther

Tim Meadows

— Station Manager

Rubén C. González

— Spike

Andrew Weiss

— Ween Bassist (uncredited)

John Weiss

— Ween Drummer (uncredited)