John Abraham
— Ajju Bhai / Ajay
Shruti Haasan
— Ranjana Shetty
Anil Kapoor
— Sagar 'Majnu' Pandey
Nana Patekar
— Uday Shankar Shetty
Paresh Rawal
— Dr. Ghunghroo
Dimple Kapadia
— Poonam
Naseeruddin Shah
— Wanted Bhai
Shiney Ahuja
— Honey
Om Puri
— Narrator (voice) (uncredited)
Rajpal Yadav
— The Tailor
Ranjeet Bedi
— Kapoor
Adi Irani
— Uday's Lawyer (uncredited)
Lauren Gottlieb
— Special Appearance in "20-20" Song
Reema Debnath
— Special Appearance in "20-20" Song
Supriya Karnik
— Payal Ghungroo
Neeraj Vora
— Badshah Khan
Surveen Chawla
— Self
Shubhi Sharma
— Self
Mushtaq Khan
— Ballu