कांटे

Amitabh Bachchan

— Yashvardhan 'Major' Rampal

Sanjay Dutt

— Ajay 'Ajju' Rehan

Suniel Shetty

— Mark Issac

Mahesh Manjrekar

— Raj ‘Bali’ Yadav

Kumar Gaurav

— Anand 'Andy' Mathur

Lucky Ali

— Maqbool ‘Mak’ Haider

JF Davis

— Det. MacQuarrie

Gulshan Grover

— Cyrus

Malaika Arora

— Lisa

Rati Agnihotri

— Major's wife

Namrata Singh Gujral

— Renu A. Mathur

Nils Allen Stewart

— Drug Dealer

Isha Koppikar

— Special Appearance in Song "Ishq Samundar"

Rohit Roy

— Special Appearance in Song "Ishq Samundar"

Tiffany Shepis

— Dancer