Jack Webb
— Joe Friday
Harry Morgan
— Bill Gannon
Vic Perrin
— Don Negler
Virginia Gregg
— Eve Kruger
Gene Evans
— Hugh Brown
John Roseboro
— Dave Bradford
Bobby Troup
— George Freeman
Tom Williams
— Melvin Gannon
Jack Ragotzy
— Carl Rockwell
Roger Til
— WIlliam Smith
Jean-Michel Michenaud
— Claude LeBorg
Bruce Watson
— Freddie
Herbert Ellis
— Rico 'Ricky' Markell
Eddie Firestone
— Max Shelton
Elizabeth Rogers
— Eve Sorenson
Kent McCord
— Brewster, Desk Clerk
Harry Bartell
— Jim Murdoch
Thordis Brandt
— Carol Freeman
Sam Edwards
— Rodman
Jimmie Horan
— Bob
Jess Kirkpatrick
— Watson
Ralph Manza
— Eddie Garcia, Police Sketch Artist
John Sebastian
— Sgt. Danny Mendez
Olan Soule
— Wayne, Forensics Officer