Juliet Stevenson
— Christine Shields
Andrew Woodall
— Martin Shields
Hugh Bonneville
— Dr. Andrew Wakefield
Adie Allen
— Dr. Carmel Wakefield
Emma Pike
— Emma
Todd Boyce
— Simonson
Felicity Montagu
— Mary Watt
Adrian Rawlins
— Dr. Tony Danielson
Harvey Virdi
— Dr. Ash's receptionist
Richard Durden
— Dr. Austen Parker
Denise Stephenson
— Red-headed woman
Gabrielle Jourdan
— Sarah
Finlay Robertson
— Journalist
Fred Pearson
— Dr. Terence Roberts
Paul Antony-Barber
— Trust director
Cate Fowler
— Headteacher