Joanne Froggatt
— Nicola Ray
Tom Riley
— Tom Ray
Phoebe Nicholls
— Tom's Mother
Michele Dotrice
— Jean
Simon Bamford
— Senior Consultant
Oliver Cunliffe
— Young Tom
Katie Pattinson
— Surgeon's Assistant
Daisy Moore
— Sarah
Alexandra Doyle
— Nurse
Isla Crowther
— Tom's Sister
Ellie Copping
— Grace Ray
Christopher Howitt
— Male Paramedic
David Carr
— Surgeon
Joey Malone
— Shy Boy
Alexander Sedgwick
— Freddy Ray (toddler)
Max Krupski
— Matt
Greg Haiste
— Tom's Father
Elsie Adams
— Freddy Ray (6 months baby)
Greta West
— Freddy Ray (newborn baby)
Gemma Layton
— Nurse
Joseph McErlean
— Tom's Brother
Jonathan Penton
— A&E Doctor
Graham Lee
— 70s Director
Natalie India Balmain
— Female Paramedic
Sophie Bephage
— P.A.