Maddie Baillio
— Tracy Turnblad
Dove Cameron
— Amber Von Tussle
Kristin Chenoweth
— Velma Von Tussle
Ariana Grande
— Penny Pingleton
Garrett Clayton
— Link Larkin
Harvey Fierstein
— Edna Turnblad
Derek Hough
— Corny Collins
Jennifer Hudson
— Motormouth Maybelle
Martin Short
— Wilbur Turnblad
Ephraim Sykes
— Seaweed J. Stubbs
Paul Vogt
— Mr. Harriman F. Spritzer
Shahadi Wright Joseph
— Little Inez
Billy Eichner
— Rob Barker
Sean Hayes
— Mr. Pinky
Andrea Martin
— Prudy Pingleton
Rosie O'Donnell
— Gym Teacher
Ricki Lake
— Pinkette
Marissa Jaret Winokur
— Pinkette
Joshua Alexander
— James
Will B. Bell
— Duane
Helene Britany
— Shelley
Riley Costello
— Brad
Kelli Erdmann
— Lou Ann
Sam Faulkner
— I.Q.
Marissa Heart
— Tammy
Joanna Jones
— Ensemble
Jacque LeWarne
— Brenda
Kamilah Marshall
— Dynamite / Peaches
Tiana Okoye
— Lorraine
Amos Oliver III
— Thad