W.E.I.R.D. World

Ed O'Neill

— Dr. Monochian

Dana Ashbrook

— Dylan Bledsoe

Marshall Bell

— Kendall

Audie England

— Diane

Paula Marshall

— Dr. Abby O'Reardon

Kathryn Morris

— Lucy

Miguel A. Núñez Jr.

— Bob Provost

Gina Ravera

— Dr. Patty Provost

Clayton Rohner

— Bryan Mayhew

Jim True-Frost

— Noah Lane

Cyia Batten

— Catherine Lane

Bryan Rush

— Janitor

Rachael Bella

— Suzie

Tony Cox

— Convenience Store Clerk

Michael Wu

— Dr. Chu, Taipei University

Stephen Liska

— Eddie

Zachary Harris

— Security Guard

Scott Nimerfro

— Albert Einstein

Karin Elena Wolf

— Bettie Page (uncredited)