Rex Lease
— Kit Cardigan / John C. Cardigan
Nancy Caswell
— Barbara Trent
Reed Howes
— Tom 'Keen' Blade
Frank McGlynn Jr.
— Gen. George A. Custer
George Chesebro
— Lt. . Frank Roberts
Lona Andre
— Belle Mead
Josef Swickard
— Maj. Henry Trent MD
Bobby Nelson
— Bobby Trent
Milburn Morante
— Buckskin - Scout
Chief Thundercloud
— Yellow Wolf
Bob Walker
— Henchman Pete
William Farnum
— James Fitzpatrick
Jack Mulhall
— Lt. Cook
Ruth Mix
— Mrs. Elizabeth Custer
Howling Wolf
— Chief Sitting Bull
High Eagle
— Chief Crazy Horse
Iron Eyes Cody
— Chief Brown Fox
Walter James
— Judge Hooker
Dorothy Gulliver
— Red Fawn
Ted Adams
— Buffalo Bill / Henchman Barney
George Morrell
— Sgt. Flanagan