Michael Opelka
— Host
Lloyd Kaufman
— Self
Michael Herz
— Self
Andrew Stevens
— Self
Samuel Z. Arkoff
— Self
John G. Avildsen
— Self
Stan Lee
— Self
Dee Dee Ramone
— Self
Joe Franklin
— Joe Franklin
Debbie Rochon
— Edna Perlmutter
Ron Fazio
— Gorgeous Guy / Toxic Avenger
Theresa Lynn
— Gorgeous Gal / Tromette
Phil Rivo
— Tromatized Host
J.J. North
— Tromette
Joan Gerardi
— Tromette
Traci Mann
— Tromette
Joe Fleishaker
— Joe Fleishaker
Jennifer Blowdryer
— Self
Andrew Deemer
— Self