Marisa Tomei
— Paula
Marley Shelton
— Rebecca
Kyra Sedgwick
— Halley
Ron Eldard
— Dag
Peter Dinklage
— Dink
Taye Diggs
— Andre
Idina Menzel
— Linda
Patrick Breen
— Peter
Sarita Choudhury
— Colleen
Zoe Caldwell
— Jessica
Kelly Cole
— Jimmy
Bruno Amato
— Joe
Sanjiv Jhaveri
— Cabbie
Zofia Borucka
— Flight Attendant
Donna Hanover
— Newscaster
Venida Evans
— Nurse
Ron Rifkin
— Dr. Fauci
Erin Fritch
— Lover
José Alvarez
— Jose
Hollis Granville
— Cabbie 2
Billy Strong
— Sal the Flight Attendant