Donald Sutherland
— Dr. Charles Eastman
Jacqueline Bisset
— Emma Eastman
Jason Lewis
— Rick Green
Saffron Burrows
— Dr. Anna Eastman
James D'Arcy
— Dr. Peter Eastman
David Wilson Barnes
— Dr. James Eastman
Gaby Hoffmann
— Dr. Sally Eastman
Jesse Bradford
— Dr. Seth Eastman
Rebecca McFarland
— Maddie Ross Eastman
Bre Blair
— Hailey Fyfe
Alexandra Holden
— Candy
Mel Rodriguez
— Mac Donnelly
Davis Desmond
— Ben
Lisa Waltz
— Heather Queenan
Ethan Phillips
— Dr. Donal Ennis
Belita Moreno
— June Lynn
Lela Lee
— Mother
Jamison Yang
— Father
Brighid Fleming
— Ivy
Colette Freedman
— Nurse #1
Jay Phillips
— Male Nurse
Mark Atteberry
— Mourner
Michael Joseph Carr
— Agent #1
Kendyl Joi
— Nurse #2
Debbie Campbell
— Sara Donnelly
Edo Walker
— Dr. Trevor Sanders