P. J. Soles
— Dr. Ramone (segment "Arbor Day")
Lloyd Kaufman
— (segment: "Hamburger! The Rapist?")
Shawn C. Phillips
— Shawn (segment "Deathrealm")
Shane Ryan-Reid
— (segment "Arbor Day")
Nathan Head
— Nathan (segment "Deathrealm")
Jessica Ann Brownlie
— The Ugly Duckling (segment "The Ugly Duckling")
Scarlet Fry
— The Gardener (segment "The Gardener")
Sadie Katz
— Allie (segment "Arbor Day")
Nicola Fiore
— (segment "Stripper Ripper")
Bryan Hanna
— Narrator / Lumberjack (segment "Arbor Day")
Rami Hilmi
— Eli (segment "Impotent Killer")
Melissa Hollett
— Melissa (segment "Deathrealm")
Maxine Wasa
— Sonya Moonshadow (segment "The Wendigo")
Jason Impey
— Woods walker / Mob Member (segment "Slaypril Fools Day Part V The Last Laugh")
Caleb Emerson
— Peanutch (segment "Hamburger! The Rapist?")
Dean Sills
— Amos (segment "Last Cabin in the Woods...of Death!")
Sarah Nicklin
— Josie La Femme (segment "Hamburger! The Rapist?")
Rebecca Gruss
— Aurora (segment "Grave of the Gods")
Tommy Pistol
— Charlie Freak (segment "Hamburger! The Rapist?")
Shaun Diston
— Black Maniac (segment "The Annum Triple Feature")
Sophia Disgrace
Michael J. Epstein
— Bad Guy #1 (segment "John Smith")
Sophia Cacciola
— Post-Apocalyptic Lady Cowboy (segment "John Smith")
Fiona Fox
— Jane (segment "The Power Tool Rapist")
Dani Thompson
— The Producer (segment "Alice in the Ultrabeyond")
Roger Gray
— The Exec Producer (segment "Alice in the Ultrabeyond")