Josh Radnor
— Sam
Malin Åkerman
— Annie
Kate Mara
— Mississippi
Zoe Kazan
— Mary Catherine
Pablo Schreiber
— Charlie
Tony Hale
— Sam #2
Michael Algieri
— Rasheen
Jakob Appelman
— School Boy
Dana Barron
— The Gynecologist
Richard Jenkins
— Paul Gertmanian
Bram Barouh
— Spencer
Sunah Bilsted
— Receptionist
Jimmy Gary Jr.
— Police Officer
Marna Kohn
— Melissa
Maria Elena Ramirez
— Jill
Peter Scanavino
— Ira
Maryann Urbano
— Social Worker
Fay Wolf
— Beth